Treatment of psoriasis with 6-substituted nicotinamides, 2-subst

Details Treatment of psoriasis with 6-substituted nicotinamides, 2-subst Treatment of psoriasis with 6-substituted nicotinamides, 2-subst

1976-08-17

1979-02-27

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424266, 424263, 546286, 546288, 546298, 546291, 546305, 546309, 546310, 546313, 546316, 546318, 546315, 544406, 544407, 544408, 544409, 544336, A61K 31455, A61K 31495

Patent

active

041419774

ABSTRACT:
A treatment to alleviate the symptoms of psoriasis consisting of topical application of a cream, ointment or lotion containing, as the principal active ingredient, one or more 6-substituted nicotinamides and or 2-substituted pyrazinamides is disclosed. The therapeutic composition may include a single member of the above active ingredients present in a total amount of from 0.01 to 5 percent by weight of the total composition, or a plurality thereof present in a preferred concentration range of from 0.02 to 2 percent by weight of the total composition. Topical application of the therapeutic composition in a cream, ointment, or a water or alcohol solution has been found to achieve from substantial to complete remissions of psoriasis in humans.

REFERENCES:
patent: 2199839 (1940-05-01), Renshaw et al.
patent: 2791534 (1957-05-01), Schaaf et al.
patent: 3337570 (1967-08-01), Sherlock et al.
patent: 3415835 (1968-12-01), Stempel et al.
Zackheim, Arch Dermatol, vol. 111, Jul. 1975, pp. 880-882.

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