Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-02-07
1987-06-23
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544122, 544123, 544316, 544317, 544318, A61K 31505, C07D23910, C07D23922
Patent
active
046753214
ABSTRACT:
Pharmaceutical compositions of specific substituted pyrimidines and methods of treatment of certain cardiovascular disorders are disclosed. Also disclosed are novel substituted acrylated pyrimidines which are useful as calcium channel blockers.
REFERENCES:
patent: 4478839 (1984-10-01), Benneche et al.
patent: 4582834 (1986-04-01), Stenzel
patent: 4596870 (1986-06-01), Benneche et al.
Folkers, et al.; J.A.C.S., 54, (1932), pp. 3751-3758.
Folkers, et al.; J.A.C.S., 55, (1933), pp. 3784-3791.
C.A., 68, (1968), Ehsan, et al., 68:78231z.
C.A., 90, (1979), Elkasaby, 90:152115n.
Hillis; Journal of Cardiovascular Medicine, Jun. 1980, pp. 583-587 and 590.
Naylor et al.; Basic Research in Cardiology 76, (1981); pp. 1-15.
Berridge; Trends in Pharmacological Sciences, 1 (1980) pp. 419-424.
Khonia, et al.; Khim Form. Zhurnal; 12(10), (1978) pp. 72-74.
Brownwald; The American Journal of Cardiology, 46, (1980), pp. 1045-1046.
Henry; The American Journal of Cardiology, 46, 1980, pp. 1047-1058.
Dangman, et al.; The American Journal of Cardiology, 46, (1980) pp. 1059-1067.
Baldwin John J.
McClure David E.
Pitzenberger Steven M.
Brust Joseph Paul
Merck & Co. , Inc.
Mitri Salvatore C.
Monaco Mario A.
Sudol Michael C.
LandOfFree
Substituted pyrimidines useful as calcium channel blockers does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted pyrimidines useful as calcium channel blockers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted pyrimidines useful as calcium channel blockers will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-721383