Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes

Details Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes

1978-02-08

1980-06-03

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546261, 546264, 252106, C07D21302, A61R 3144

Patent

active

042062152

ABSTRACT:
Bis-[4-(R-amino)-1-pyridinium]alkanes are prepared by reacting a 4-(R-amino)pyridine with an appropriate disubstituted alkane. The compounds are useful as antimicrobial agents. Certain species are also useful as dental plaque-preventive agents.

REFERENCES:
patent: 3055902 (1962-09-01), Walker
patent: 3786058 (1974-01-01), Edwards
Walker et al., J. Org. Chem., vol. 26, pp. 2740-2747, (1961).
Austin, J. Pharm. Pharmacol., vol. 11, pp. 80-93, (1959).

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