Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-05-18
1988-08-02
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514220, 540556, 540576, 544373, 548469, A61K 31495, C07D40304
Patent
active
047614110
ABSTRACT:
The invention relates to dihydrobenzopyrrolobenzodiazepines of the formula ##STR1## where X and Y may be the same or different and each is hydrogen, halogen, CF.sub.3, lower alkyl, lower alkoxy, lower alkylthio and lower alkylsulfonyl; R.sub.1 is hydrogen when R.sub.2 is bonded to R.sub.3 to form a --CH.sub.2 CH.sub.2 -- group; and R.sub.3 is hydrogen when R.sub.1 is bonded to R.sub.2 to form a --CH.sub.2 CH.sub.2 -- group and the pharmaceutically acceptable acid addition salts thereof.
REFERENCES:
patent: 4186199 (1980-01-01), Glamkowski et al.
patent: 4192874 (1980-03-01), Glamkowski et al.
Glamkowski, Chemical Abstract, vol. 93, p. 941, 46733q, Equivalent to U.S. Pat. No. 4,192,874.
Glamkowski, Chemical Abstract, vol. 93, p. 851, Z39373f.
Merck Index, p. 310, 2374, (9th Edition).
Chiang Yulin
Glamkowski Edward J.
Daus Donald G.
Hoechst-Roussel Pharmaceuticals Inc.
Shen Cecilia
Wittekind Raymond R.
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