Isoxazolopyrimidine derivatives

Details Isoxazolopyrimidine derivatives Isoxazolopyrimidine derivatives

1983-03-04

1985-03-12

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48704, A61K 31505

Patent

active

045046620

ABSTRACT:
Isoxazolo[3,4-d]pyrimidines of the formula ##STR1## wherein R.sup.1 and R.sup.2, respectively, are lower alkyl; R.sup.3 is lower alkyl or acyl; and R.sup.4 is hydrogen, lower alkyl, or acyl have antiflammatory, analgesic and antipyretic activities in mammals and low acute and subacute toxicities, as well. The compounds are particularly useful as an antiinflammatory, analgesic and antipyretic drug.

REFERENCES:
patent: 2957875 (1960-10-01), Lyttle et al.
patent: 3056781 (1962-10-01), Papesch
patent: 3094529 (1963-06-01), Klosa
patent: 3114751 (1963-12-01), Whetstone
patent: 3536711 (1970-10-01), Dunn et al.
patent: 3959280 (1976-05-01), Furukawa et al.
patent: 4052391 (1977-10-01), Furukawa et al.
patent: 4129654 (1978-12-01), Marumoto et al.
patent: 4202975 (1980-05-01), Marumoto et al.
Hirota et al., Chemical Abstracts, vol. 95, 150,597a (1981).

Affiliated with

Also associated with

Rating

Isoxazolopyrimidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isoxazolopyrimidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoxazolopyrimidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-709042