Transmembrane glycoprotein ASGP-2: nucleotide sequences and reco

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 693, 4351721, 4352523, 435325, 4353201, 536 235, 530395, C12N 1512

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056248164

ABSTRACT:
The present invention relates, in general, to a glycoprotein that is a member of the epidermal growth factor superfamily ASGP-2. In particular, the present invention relates to a DNA segment encoding the glycoprotein; to a recombinant DNA molecule containing the DNA segment; to cells containing the recombinant DNA molecule; to a method of producing the glycoprotein; and to methods of disease diagnosis and therapy that involve the use of the glycoprotein or DNA segment encoding same.

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Carothers Carraway et al. "Association of p185.sup.new with Microfilaments via a Large Glycoprotein Complex in Mammary Carcinoma Microvilli", The Journal of Biological Chemistry, vol. 268, No. 8, pp. 5582-5587, Mar. 15, 1993.
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