Liposoluble heterocyclic compounds useful as magnetic resonance

Details Liposoluble heterocyclic compounds useful as magnetic resonance Liposoluble heterocyclic compounds useful as magnetic resonance

1995-06-07

1997-04-29

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

514184, 514836, 435173, 534 16, 544 64, 544225, 546 2, 548101, 549210, A61B 5055

Patent

active

056246625

ABSTRACT:
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other additives. The lipids may be in the form of liposomes, micelles or lipid emulsions. The contrast agents of the invention have particular use in magnetic resonance imaging of the liver, blood pool and reticuloendothelial system.

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