Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Enzyme inactivation by chemical treatment
Patent
1984-10-01
1987-05-26
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Enzyme inactivation by chemical treatment
435 29, 435188, 435810, C12N 999, C12N 996, C12Q 128
Patent
active
046686304
ABSTRACT:
An improved composition of the type comprising a known concentration of at least one enzyme. The composition is characterized in that substantially all of at least one of the enzymes is combined with a stabilizing amount of a reversible inhibitor thereof to form an inhibitor-enzyme complex, thereby stabilizing the enzyme moiety of the complex.
A method of stabilizing a composition comprising a known concentration of at least one enzyme. The method comprising combining substantially all of at least one of the enzymes with a stabilizing amount of a reversible inhibitor thereof to form an inhibitor-enzyme complex, thereby stabilizing the enzyme moiety of the complex.
REFERENCES:
patent: 3956069 (1976-05-01), Allain et al.
C. Abstracts I: 68:103355c Clin. Chim. Acta 20(1) 7-10.
Chemical Abstracts II: 99:171969w Int. J. Biochem. 1983, 15(10), 1279-1282.
Chemical Abstracts III: 97:19656t Biochem. J. 1982, 202(3), 581-587.
Abers Julia E.
Beckman Instruments Inc.
Grant Arnold
May W. H.
Nucker Christine M.
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