DNA vaccines for herpes simplex virus

Details DNA vaccines for herpes simplex virus DNA vaccines for herpes simplex virus

1997-10-23

1999-09-28

Ketter, James

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

530395, 536231, 536 2372, 4241861, 4242291, A61K 4800

Patent

active

059588950

ABSTRACT:
Protective and therapeutic vaccines are disclosed. Vaccines for preventing or treating herpes simplex virus infection are disclosed. Methods for preventing herpes simplex virus infection and treating individuals who have been infected with herpes simplex virus and to compositions for and methods of making prophylactic and therapeutic vaccines for herpes simplex virus are disclosed.

REFERENCES:
patent: 5612041 (1997-03-01), Burke et al.
patent: 5654174 (1997-08-01), Cohen et al.
Z. Xiang et al, "Immune Responses to Nucleic Acid Vaccines to Rabies Virus", Virology, 209:569-579 (1995).
G. Inchauspe et al, "Immune Responses Against Hepatitis C Virus Structural Proteins Following Genetic Immunisation", Dev. Biol. Stand., 92:163-168 (1998).
G. Inchauspe et al, "Plasmid DNA Expressing a Secreted or a Nonsecreted Form of Hepatitis C Virus Nucleocapsid: Comparative Studies of Antibody and T-Helper Responses Following Genetic Immunization", DNA and Cell Biol., 16(2):185-195 (1997).
R. Johnson et al, "Herpes Simplex Virus Glycoprotein D is Recognized as Antigen by CD4+ and CD8+ T Lymphocytes from Infected Mice", J. Immunol., 145(2):702-710 (Jul. 15, 1990).
H. Ghiasi et al, "Expression of Seven Herpes Simplex Virus Type 1 Glycoproteins (gB, gC, gE, gG, and gI): Comparative Protection Against Lethal Challenge in Mice", J. Virol., 68(4):2118-2126 (Apr. 1994).
G. Inchauspe et al, "Plasmid DNA Expressing a Secreted or a Nonsecreted Form of Hepatitis C Virus Nucleocapsid: Comparative Studies of Anitbody and T-Helper Responses Following Gentic Immunization", DNA Cell Biol., 16(2):185-195 (Feb. 1997)(Abstract only).
Z. Xiang et al, "Immune Responses to Nucleic Acid accines to Rabies Virus", Virology, 209(2):569-579 (Jun. 1, 1995)(Abstract only).
PCT International Search Report, Mailed Mar. 4, 1998, 4 pages.
Cohen, Gary H. et al., "Expression of Herpes Simplex Virus Type 1 Glycoprotein D Deletion Mutants in Mammalian Cells," Journal of Virology, Jun. 1988, vol. 62, No. 8, pp. 1932-1940.
Chiang, Hsien-Yuan et al., "Identification of Functional Regions of Herpes Simplex Virus Glycoprotein gD by Using Linker-Insertion Mutagensis," Journal of Virology, Apr. 1994, vol. 68, No. 4 pp. 2529-2543.
Nicola, Anthony V. et al., "Structure-Function Analysis of Soluble Forms of Herpes Simplex Virus Glycoprotein D," Journal of Virology, Jun. 1996, vol. 70, No. 6, pp. 3815-3822.
Berman et al. The Journal of Infectious Diseases. vol., 157, pp. 897-901, May 1988.
Lasky et al. Bio/Technology. pp. 527-532, Jun. 1984.
Watson, R.J. Gene. vol. 26, pp. 307-312, 1983.
Orkin et al. Report and Recommendations of the Panel to assess the NIH investment in research on gene therapy, Dec. 1995.
Crystal, R. Science. vol. 270, pp. 404-410, 1995.
Berman et al. Science. vol. 227, pp. 1490-1492, Mar. 1985.
Yokoyama et al. FEMS Immunology and Medical Microbiology. vol. 14, pp. 221-230, 1996.
Chattergoon et al. The FASEB Journal. vol. 11, pp. 753-763, Aug. 1997.
Webster et al. Biodrugs. vol. 4, pp. 273-292, Oct. 1997.

Affiliated with

Also associated with

Rating

DNA vaccines for herpes simplex virus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA vaccines for herpes simplex virus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA vaccines for herpes simplex virus will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-703283