Cell culture incubator

Details Cell culture incubator Cell culture incubator

1998-08-04

1999-09-28

Beisner, William H.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

435809, 312 31, 3122571, 312108, 312236, 220 428, C12M 102

Patent

active

059587636

ABSTRACT:
A cell culture incubator has a chamber divided into an incubation portion and a control portion. The incubation portion is adapted to contain a cell culture receptacle. A cell culture receptacle agitator is located in the control portion of the incubator and linkage between the cell culture receptacle agitator and the incubation portion of the chamber causes agitation of the cell culture receptacle. A heater in the control portion of the chamber heats air from the external environment and transports the heated air to the incubation portion of the chamber. A wall divides the chamber into the incubation portion and the control portion. The heater may be a forced air heater that provides a positive pressure to the incubation portion of the chamber to reduce contamination in the incubation portion. A nutrient and gas circulation system communicates with the cell culture receptacle in the incubation portion of the chamber. The nutrient and gas circulation system includes a gas source external to the incubation portion of the chamber and tubing provides communication between the gas source, the cell culture receptacle in the incubation portion of the chamber, and nutrient media. A filter in an opening of the incubation portion of the chamber communicates with the tubing to remove contaminants from gas emanating from the cell culture receptacle prior to venting to the external environment.

REFERENCES:
patent: 3536611 (1970-10-01), de Filippi et al.
patent: 3821087 (1974-06-01), Knazek et al.
patent: 3860309 (1975-01-01), Brendgrod
patent: 3883393 (1975-05-01), Knazek et al.
patent: 4033825 (1977-07-01), Haddad et al.
patent: 4061736 (1977-12-01), Morris et al.
patent: 4184922 (1980-01-01), Knazek et al.
patent: 4220725 (1980-09-01), Knazek et al.
patent: 4250266 (1981-02-01), Wade
patent: 4329431 (1982-05-01), Youssef
patent: 4391912 (1983-07-01), Yoshida et al.
patent: 4537860 (1985-08-01), Tolbert et al.
patent: 4720462 (1988-01-01), Rosenson
patent: 4868122 (1989-09-01), Kominek et al.
patent: 5061448 (1991-10-01), Mahe et al.
patent: 5278063 (1994-01-01), Hubbell et al.
patent: 5290700 (1994-03-01), Binot et al.
patent: 5360741 (1994-11-01), Hunnell
patent: 5424209 (1995-06-01), Kearney
patent: 5455175 (1995-10-01), Wittwer et al.
patent: 5459058 (1995-10-01), Leder et al.
patent: 5622857 (1997-04-01), Goffe
Custer, L.M., Ph.D. Chem. Engr. Dissertation: Physiological studies of hybridoma cultivation in hollow fiber bioreators, UCB, 1988, pp. 15, 49, 69, 83, 103, 106-108, 115, 181-182, 193-197, 201, and 221-223.
Oudshoorn, A., Presentation Multiple Fiber Bioreactor on distributor training, Dec. 10, 1991.
Oh, D.J., el al., High density culture of hybridoma cells in a dual hollow fiber bioreactor, Biotechnology Techniques, 6(1):77-82, 1992.
Fresenias, A.G., et al., Autoklavierbares Hollow Fiber Bioreaktormodul mit intergrierter Basgasung, Biotech GmbH & Co., 1993.
Hohlfaster-Reaktor fur Humanzellen, B-L Journal, 4:3, Jul. 1993.
Cousins, R.B., et al., A dual fibre membrane reactor for the cultivation of mammalian cells. No Date provided.

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