Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-07-08
1999-09-28
Elliott, George C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 691, 43525233, 4353201, 536 235, C12Q 168, C12P 2102, C12N 121, C12N15412
Patent
active
059586907
ABSTRACT:
The invention provides a human TSC-22 homolog (HTSCH) and polynucleotides which identify and encode HTSCH. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HTSCH.
REFERENCES:
Buschs, S.J. et al., "Dimers, leucine zippers and DNA-binding domains", Trends Genet., 6: 36-40 (1990).
Shibanuma, M. et al., "Isolation of a Gene Encoding a Putative Leucine Zipper Structure That Is Induced by Transforming Growth Factor .beta.1 and Other Growth Factrors", J. Biol. Chem., 267 : 10219-10224 (1992).
Vogel, P. et al., "hDIP --a potential transcriptional regular related to murine TSC--22 and Drosophila shortsighted (shs)-is expressed in a large number of human tissues", Biochim. Biophy. Acta., 1309: 200-204 (1996).
Jay, P. et al., "Cloning of the Human Homologue of the TGF.beta.--Stimulated Clone 22 Gene", Biochem. Biophy. Res. Commun., 222 : 821-826 (1996).
Jay, P. et al., (Direct Submission) , GenBank Sequence Database (Accession 1407597) , National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1407597) Jun. 26, 1996.
Ohta, S. et al., (Direct Submission) , GenBank Sequence Database (Accession 1871130) , National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1871130) Mar. 5, 1997.
Treisman, J.E., et al., (Direct Submission) , GenBank Sequence Database (Accession 833708) , National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 833708) Sep. 29, 1995.
Treisman, J.E., et al., (Direct Submission) , GenBank Sequence Database (Accession L42511) , National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 833707) Sep. 29, 1995.
Ohta et al. (1996) Molecular cloning and characterization of a transcription factor for the C-type natriuretic peptide gene promoter. Eur. J. Biochem. 242:460-466, Dec. 1996.
Hillman Jennifer L.
Lal Preeti
Shah Purvi
Elliott George C.
Incyte Pharmaceuticals Inc.
Murry Lynn E.
Schwartzman Robert
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