Substituted phenyl piperidines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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546238, 546240, 546246, 546236, 546233, C07D21134, C07D21122, C07D21132, A61K 31445

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active

044263864

ABSTRACT:
Compounds of the formula ##STR1## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group, or a possibly substituted phenyl group, R.sup.2 is an alkyl, phenethyl, benzyl or phenyl group, R.sup.3 is H or an alkyl group and R.sup.4 is an allyl or benzyl group, and R is an alkyl, hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group or alkenyl group, processes for their preparation and pharmaceutical preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.

REFERENCES:
patent: 2892842 (1959-06-01), McElvain
Chemical Abstracts 69: 86776s (1968) citing Julia, M., et al. Bull. Soc. Chim. Fr. 1968, (3), 1000-1007.

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