Extruded orally administrable opioid formulations

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424456, 424468, 424489, 5147723, 5147726, 514781, 514784, A61K 916, A61K 922, A61K 952

Patent

active

059584521

ABSTRACT:
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.

REFERENCES:
patent: Re33093 (1989-10-01), Schiraldi et al.
patent: 2743303 (1956-03-01), Blythe et al.
patent: 3065143 (1962-11-01), Christenson et al.
patent: 3652589 (1972-03-01), Flick et al.
patent: 3714350 (1973-01-01), Gough
patent: 3830934 (1974-08-01), Flick et al.
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3880991 (1975-04-01), Yolles
patent: 3950508 (1976-04-01), Mony et al.
patent: 3965256 (1976-06-01), Leslie
patent: 3974157 (1976-08-01), Shetty et al.
patent: 4013784 (1977-03-01), Speiser
patent: 4076798 (1978-02-01), Casey et al.
patent: 4132753 (1979-01-01), Blichare et al.
patent: 4173417 (1979-11-01), Kruder
patent: 4230687 (1980-10-01), Sair et al.
patent: 4259314 (1981-03-01), Lowey
patent: 4265875 (1981-05-01), Byrne et al.
patent: 4292300 (1981-09-01), Byrne et al.
patent: 4310483 (1982-01-01), Dorfel et al.
patent: 4343789 (1982-08-01), Kawata et al.
patent: 4344431 (1982-08-01), Yolles
patent: 4346709 (1982-08-01), Schmitt
patent: 4366172 (1982-12-01), Lednicer
patent: 4374082 (1983-02-01), Hochschild
patent: 4380534 (1983-04-01), Fukui et al.
patent: 4389393 (1983-06-01), Schor et al.
patent: 4406883 (1983-09-01), Byrne et al.
patent: 4421736 (1983-12-01), Walters et al.
patent: 4483847 (1984-11-01), Augart
patent: 4533562 (1985-08-01), Ikegami et al.
patent: 4613619 (1986-09-01), Sleigh et al.
patent: 4621114 (1986-11-01), Watanabe
patent: 4649042 (1987-03-01), Davis et al.
patent: 4720384 (1988-01-01), DiLuccio et al.
patent: 4764378 (1988-08-01), Keith et al.
patent: 4778676 (1988-10-01), Yang et al.
patent: 4801458 (1989-01-01), Hidaka et al.
patent: 4801460 (1989-01-01), Goertz et al.
patent: 4806337 (1989-02-01), Snipes et al.
patent: 4818450 (1989-04-01), Hall et al.
patent: 4828836 (1989-05-01), Elger et al.
patent: 4834984 (1989-05-01), Goldie et al.
patent: 4842761 (1989-06-01), Rutherford
patent: 4844907 (1989-07-01), Elger et al.
patent: 4844909 (1989-07-01), Goldie et al.
patent: 4861598 (1989-08-01), Oshlack
patent: 4879108 (1989-11-01), Yang et al.
patent: 4880585 (1989-11-01), Klimesch et al.
patent: 4880830 (1989-11-01), Rhodes
patent: 4882151 (1989-11-01), Yang et al.
patent: 4882152 (1989-11-01), Yang et al.
patent: 4882153 (1989-11-01), Yang et al.
patent: 4882155 (1989-11-01), Yang et al.
patent: 4882156 (1989-11-01), Yang et al.
patent: 4882157 (1989-11-01), Yang et al.
patent: 4882159 (1989-11-01), Yang et al.
patent: 4882167 (1989-11-01), Jang
patent: 4894234 (1990-01-01), Sharma et al.
patent: 4917899 (1990-04-01), Goeghegan et al.
patent: 4925675 (1990-05-01), Giannini et al.
patent: 4935246 (1990-06-01), Ahrens
patent: 4957681 (1990-09-01), Klimesch et al.
patent: 4959208 (1990-09-01), Chakrabarti et al.
patent: 4967486 (1990-11-01), Doelling
patent: 4970075 (1990-11-01), Oshlack
patent: 4987136 (1991-01-01), Kreek et al.
patent: 4990341 (1991-02-01), Goldie et al.
patent: 4992100 (1991-02-01), Koepff et al.
patent: 4994227 (1991-02-01), Dietz et al.
patent: 5007790 (1991-04-01), Shell
patent: 5013306 (1991-05-01), Solomon et al.
patent: 5023089 (1991-06-01), Sakamoto et al.
patent: 5026560 (1991-06-01), Makino et al.
patent: 5030400 (1991-07-01), Danielson et al.
patent: 5035509 (1991-07-01), Kruder
patent: 5049394 (1991-09-01), Howard et al.
patent: 5055307 (1991-10-01), Tsuru et al.
patent: 5073379 (1991-12-01), Klimesch et al.
patent: 5102668 (1992-04-01), Eichel et al.
patent: 5126145 (1992-06-01), Evenstad
patent: 5132142 (1992-07-01), Jones et al.
patent: 5133974 (1992-07-01), Paradissis et al.
patent: 5162117 (1992-11-01), Stupak et al.
patent: 5165952 (1992-11-01), Solomon et al.
patent: 5167964 (1992-12-01), Muhammed et al.
patent: 5169645 (1992-12-01), Shukla et al.
patent: 5178868 (1993-01-01), Malmqvist-Granlund et al.
patent: 5183690 (1993-02-01), Carr et al.
patent: 5196203 (1993-03-01), Boehm
patent: 5202128 (1993-04-01), Morella et al.
patent: 5204119 (1993-04-01), Shiobara et al.
patent: 5229148 (1993-07-01), Copper
patent: 5234697 (1993-08-01), Sipos
patent: 5240400 (1993-08-01), Fujimoto et al.
patent: 5262172 (1993-11-01), Sipos
patent: 5266331 (1993-11-01), Oshlack et al.
patent: 5271934 (1993-12-01), Goldberg et al.
patent: 5273758 (1993-12-01), Royce
patent: 5283065 (1994-02-01), Doyon et al.
patent: 5290560 (1994-03-01), Autant
patent: 5292461 (1994-03-01), Juch et al.
patent: 5296266 (1994-03-01), Kunugi et al.
patent: 5300300 (1994-04-01), Egidio et al.
patent: 5340581 (1994-08-01), Tseng et al.
patent: 5350584 (1994-09-01), McClelland et al.
patent: 5354856 (1994-10-01), Kawashima et al.
patent: 5356635 (1994-10-01), Raman et al.
patent: 5378462 (1995-01-01), Boedecker
patent: 5380535 (1995-01-01), Geyer et al.
patent: 5395626 (1995-03-01), Kotwal et al.
patent: 5403593 (1995-04-01), Royce
patent: 5443846 (1995-08-01), Yoshioka et al.
patent: 5451424 (1995-09-01), Solomon et al.
patent: 5453283 (1995-09-01), Munch et al.
patent: 5456923 (1995-10-01), Nakamichi et al.
patent: 5472710 (1995-12-01), Klokkers-Bethke et al.
patent: 5476528 (1995-12-01), Trimm et al.
patent: 5478577 (1995-12-01), Sackler et al.
patent: 5510114 (1996-04-01), Borella et al.
patent: 5516205 (1996-05-01), Oda et al.
patent: 5552159 (1996-09-01), Mueller et al.
patent: 5567439 (1996-10-01), Myers et al.
R. Kinget, et al., "Preparation and Properties of Granulates Containing Solid Dispersions", Acta Phar. Tech., vol. 31, No. 2, 1985, pp. 57-62.
M.J. Jozwiakowski et al., "Characterization of a Hot-Melt Fluid Bed Coating Process for Fine Granules", Pharm. Research, vol. 7, No. 11, 1990, pp. 1119-1124.
M. Niskanen et al., "Pelletization in a Centrifugal Granulator, Part I:Effects of Binder-Solution Concentration", Pharm. Tech. Int'l., Oct. 1990, pp. 22-38.
L. Lachman et al., "The Theory and Practice of Industrial Pharmacy", p. 315, Lea & Febiger, Phi. 1976.
FDA Guide to Inspections of Oral Solid Dosage Forms Pre/Post Approval Issues for Development and Validation, Jan. 1994.
T. Schaefer et al., "Melt Pelletization in a High Shear Mixer I Effects of Process Variables and Binder", Acta Pharm. Nord. vol. 4, No. 3, pp. 133-140, 1992.
T. Schaefer et al., "Melt Pelletization in a High Shear Mixer II Power Consumption and Granule Growth", Acta Pharm. Nord. vol. 4, No. 3, pp. 141-148, 1992.
T. Schaefer, et al., "Melt Granulation in a Laboratory Scale High Shear Mixer", Drug Dev. and Indust. Phar., vol. 16, No. 8, pp. 1249-1277, 1990.
McTaggart, C.M. et al., "The Evaluation of Formulation and Processing Conditions of a Melt Granulation Process", Int'l. J. Pharm. vol. 19, No. 2, issued 1984, pp. 139-148.
El-Shanawany, S., "Sustained Release of Nitrofurantion From Inert Wax Matrixes", J. Controlled Release, vol. 26, No. 1, issued 1993, pp. 11-19.
P. Flanders, et al., "The Control of Drug Releases From Conventional Melt Granulation Matrices", Drug. Dev. and Industrial Pharm., vol. 13, No. 6, pp. 1001-1022, 1987.
Thomsen, L. Juul, "Matrix Pellets Prolonged Formulations Prepared by Melt Pelletization", Dept. of Pharm. Royal Danish School of Pharmacy, 1992.
Thomsen,L. Juul, et al., "Prolonged Release Matrix Pellets Prepared by Melt Pelletization I. Process Variables", Drug Development and Industrial Pharmac y, vol. 19, No. 15, pp. 1867-1887 (1993).
Thomsen, L. Juul, et al., "Prolonged Release Matrix Pellets Prepared by Melt Pelletization II. Hydrophobic Substances as Meltable Binders", Drug Development and Industrial Pharmacy, vol. 20, No. 7, pp. 1179-1197 (1994).
Thomsen, L. Juul, "Utilizing melt pelletization tequnique for the preparation of prolonged release products", Pelletization, (material elaborated by assistant Prof. Lars Juul Thomsen, Dept. of Pharmaceutics, Royal Danish School of Pharmacy for the DIE course "Pelletization Technology", Nov. 1992, 106 pages plus appendixes.
Thomsen, L. Juul, "Prolonged Matrix Pellets Prepared by Melt Pelletization. Part IV:Drug Content, Drug Particle Size and Binder Composition", Pharmaceutical Technology Europa, pp. 19-22 (Oct.

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