N-(4-substituted-3,5-dichloro-phenyl)-piperazines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

544389, 544391, 544395, C07D29514, C07D29520, C07D29512

Patent

active

041396219

ABSTRACT:
1-(3,5-Dichlorophenyl)piperazines bearing a fluoro, chloro, methyl, nitro, hydroxy, methoxy, cyano, amino, methylamino or dimethylamino substituent in the 4-position of the phenyl ring and being further optionally substituted in the 4-position of the piperazine ring by tetrahydropyranyl, alkyl, formyl, carboxy, alkanoyl or carboalkoxy, and the acid addition salts thereof, are tranquilizers. A typical embodiment is 1-(3,4,5-trichlorophenyl)piperazine hydrochloride.

REFERENCES:
patent: 3775313 (1973-11-01), Adams et al.
patent: 3988456 (1976-10-01), Nishimura et al.

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