6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrim

Details 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrim 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrim

1977-08-19

1979-02-13

Rosen, Sam

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424251, 42424856, A61K 31535, A61K 31505, A61L 904

Patent

active

041396197

ABSTRACT:
This invention relates to a process for stimulating the growth of mammalian hair comprising the application to mammalian skin of a compound of the formula: ##STR1## wherein R.sub.1 is a moiety selected from the group consisting of moieties of the formula ##STR2## wherein R.sub.3 and R.sub.4 are selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower aralkyl, and lower cycloalkyl, and taken together R.sub.3 and R.sub.4 may be a heterocyclic moiety selected from the group consisting of aziridinyl, azetidinyl, pyrrolidinyl, piperidino, hexahydroazepinyl, heptamethylenimino, octamethylenimino, morpholino, and 4-lower-alkylpiperazinyl, each of said heterocyclic moieties having attached as substituents on the carbon atoms 0-3 lower alkyl groups, hydroxy or alkoxy wherein R.sub.2 is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkoxyalkyl, lower cycloalkyl, lower aryl, lower aralkyl, lower alkaryl, lower alkaralkyl, lower alkoxyaralkyl, and lower haloaralkyl and the pharmacologically acceptable acid addition salts thereof in association with a topical pharmaceutical carrier.

REFERENCES:
patent: 3461461 (1969-08-01), Anthony et al.

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