Process for pyrrolidinyl hydroxamic acid compounds

Details Process for pyrrolidinyl hydroxamic acid compounds Process for pyrrolidinyl hydroxamic acid compounds

1999-08-16

2000-02-29

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20712

Patent

active

060311142

ABSTRACT:
A method for preparing hydroxamic acid derivatives which are useful as analgesic, antiinflammatory, or neuroprotective agents.

REFERENCES:
Tetrahedron Letters, vol. 37, No. 31, pp. 5619-5622, 1996, O'Brien, et al., "A Simple and Efficient Method for the Preparation of homochiral Amines: Application to the Synthesis of a New C.sub.2 Symmetric Triamine".
J. Org. Chem., 1995, 60, 8424-8427, Miao, et al, "Influence of the Aromatic Substituent on the Reactivity of (R)-N-Methyl-1-phenyl-2-(1-piperidinyl)ethanamine Cuprates in Enantioselective Conjugate Addition.sup.1 ".
Tetrahedron: Asymmetry, vol. 8, No. 15, pp. 2613-2618, 1997, de Sousa, et al, Two uselful methods for the preparation of (R)-and (S)-N-methyl-1-phenyl-2-(1-pyrrolidinyl)enthanamine.
Letters Synlett, Feb. 1990, pp. 109-110, Synthesis of Chiral Triamine Ligands from Ephedrine and Pseudoephedrine.

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