Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1985-09-09
1987-06-16
Marantz, Sidney
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
422 57, 422 61, 435 34, 435810, 436519, 436543, C12Q 114
Patent
active
046736395
ABSTRACT:
The present invention is a ready-to-use microtube and method for the simple and accurate identification of beta-hemolytic streptococci from inoculated swabs. Non-volatile reagents are selected and affixed to two separate loci within the microtube by means of a stable, water-soluble or -dispersible binder. At the time of patient examination, the patient site (pharynx, etc.) is swabbed and the swab is placed, tip down, in the prepared microtube. Four to six drops of distilled water are added, the swab is rotated and, after a brief incubation period, an agglutination agent is used to verify the presence or absence of a specific streptococcus group antigen by the presence or absence of a visible agglutination. The test is suitable for use in identifying any streptococcus group which bears antigens susceptible to extraction by nitrous acid, including in particular the clinically significant group A, B, C, F, and G beta-hemolytic streptococci.
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"Identification of Group C Streptococcal Antigen Extracts with Lectin-Bound Polystyrene Particles", Journal of Clinical Microbiology, Jan., 1984, pp. 83-84, vol. 19, No. 1, Malcolm Slifkin and Gail M. Gil.
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Allegheny-Singer Research Institute
Marantz Sidney
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