Sorbent families

Details Sorbent families Sorbent families

1994-05-24

1997-02-04

Nucker, Christine M.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

530364, 530368, 530412, 530415, 530416, A61K 3804, C07K 700

Patent

active

055999018

ABSTRACT:
Compounds useful as affinity chromatography supports and as labeled reagents are disclosed. The compounds are peptides which can be constituted in families of positively charged, negatively charged or uncharged small peptides or the amidated forms thereof with varying characteristics as to charge, charge distribution, hydrophobicity, cyclization, and helical conformation propensity.

REFERENCES:
patent: 4694044 (1987-09-01), Kiniwa
patent: 4963263 (1990-10-01), Kauvar
Ohlson et al., "Novel approach to affinity chromatography using 'weak" monoclonal antibodies" Analytical Biochemistry (1988) 169:204-208.
M uller et al., "New ion exchangers for the chromatography of biopolymers" Journal of Chromatography (1990) 510:133-140.
Smith et al., (1983) Principles of Biochemistry, Seventh Ed., McGraw-Hill, New York, pp. 77-78. see "Prediction of secondary structure".
Garland R. Marshall; Three-dimensional structure of peptide complexes: implications for recognition; Current Opinion in Structural Biology (1992) 2:904-919.

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