Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-10-07
1976-05-04
Narcavage, Joseph A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424250, C07D29512
Patent
active
039547655
ABSTRACT:
Piperazine derivatives of the formula: ##SPC1##
Wherein n is 0 or 1, X is oxygen or sulfur, R and R', which are the same or different, are hydrogen or lower alkyl and: ##SPC2##
Is always bonded to the benzene ring.
These compounds are used as medicine especially in the treatment of peripheral vascular disorders, Parkinson's disease, hypertension and pain.
REFERENCES:
patent: 3808212 (1974-04-01), Renth et al.
E. Merck A.G., Chemical Abstracts, Vol. 66, p. 2587u, (1967).
Burger, Medicinal Chemistry, 3rd Ed., pp. 636 and 638 Part I and p. 1588 Part II.
Canevari Roger
Laubie Michel
Poignant Jean-Claude
Regnier Gilbert
Hueschen Gordon W.
Narcavage Joseph A.
Science-Union et Cie
Tovar Jose
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