Antigenic polypeptides of Taenia ovis

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4241851, 4242661, 4352523, 43525233, 4353201, 530350, 5303871, 530395, 536 235, C12N 1512, C07K 14435, A61K 3900

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055996922

ABSTRACT:
This invention relates to polypeptide antigens of T.ovis suitable for use in vaccines to protect ruminants against infection by cestode parasites. The antigens are preferably obtained by expression of DNA coding therefor in a recombinant host cell. Aspects of the invention include DNA encoding the antigens, vectors containing the DNA and hosts which express the antigens.
The invention also provides antibody and DNA probes for use in identifying protective antigens of cestode parasites other than T.ovis.

REFERENCES:
patent: 5366728 (1994-11-01), Harrison et al.
J. Mol. Biochem. Parasitol, 1988, 28 (1988), pp. 21-30.
Nature, 1989, 338 (621), pp. 585-587.
Adv. Parasitology, 21, (1982), pp. 230-296.
Howell, M. J. et al. "Cloning and expression of T. ovis . . . " Mol. Biochem. Parasitol, 28, pp. 21-30.
Craig, P. S. et al. "Antibody responses . . . " Z. Parasitol, 67 (2), pp. 197-209.
Osborn, P. J. et al. "Vaccination of . . . " Res. Vet. Sci. 32 (3) 1982) (Abstract only), pp. 350-353.

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