Methods for lowering serum cholesterol and inhibiting smooth mus

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5142335, 514320, 514253, 514456, A61K 3154, A61K 4336

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active

054079551

ABSTRACT:
The present invention provides novel methods of lowering serum cholesterol and inhibiting smoother muscle cell proliferation, particularly restenosis, in humans, and inhibiting uterine fibroid disease and endometriosis in women comprising administering to a human/woman in need of treatment an effective amount of a compound of formula I ##STR1## wherein R is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halo, or trifluoromethyl;

REFERENCES:
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patent: 3535344 (1970-10-01), Irmscher et al.
patent: 3882287 (1974-07-01), Bolger et al.
patent: 4945086 (1990-07-01), Benitz et al.
patent: 4988735 (1991-01-01), Casagrande et al.
patent: 5283257 (1994-02-01), Gregory et al.
U.S. Patent Application 08/148,786, filed Nov. 1993.
U.S. Patent Application 08/148,038 filed Nov. 1993.

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