Intermediates in the synthesis of prostaglandins

Details Intermediates in the synthesis of prostaglandins Intermediates in the synthesis of prostaglandins

1975-07-25

1976-11-16

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260309, 260343, 2603433R, 260413, 260514D, C07D31772

Patent

active

039924130

ABSTRACT:
The invention relates to a new and novel synthesis of prostaglandin E.sub.2, and it particularly relates to a novel process starting with relatively inexpensive starting materials. The invention further relates to a synthesis which is readily adaptable for large scale processing because of the high yields in the individual reaction steps.
The invention further relates to novel compounds formed as intermediates in the synthesis of prostaglandin E.sub.2. The invention still further relates to synthetic analogs and known metabolites of prostaglandin E.sub.2 and prostaglandin E.sub.1, useful as standards in certain biological assays for determining prostaglandin-like activity.

REFERENCES:
patent: 3833612 (1974-09-01), Wendler et al.

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