N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furany

Details N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furany N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furany

1987-09-17

1989-04-11

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546283, C07D40100, A61K 3144

Patent

active

048207187

ABSTRACT:
The invention discloses certain N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts useful as PAF inhibitors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-induced blood platelet aggregation, PAF-mediated bronchoconstriction and extravasation, PAF-induced hypotension, PAF-induced ischemic bowel disease and PAF-mediated, endotoxin-induced lung injury.

REFERENCES:
patent: 4711892 (1987-12-01), Manoury et al.

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