Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-01-09
1989-10-03
Shaver, Paul F.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514492, A61K 31555
Patent
active
048717290
ABSTRACT:
A bis-platinum complex having the structure: ##STR1## wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt.sup.2+. The complexes are useful in the inhibition of tumors.
REFERENCES:
patent: 4225529 (1980-09-01), Hydes et al.
patent: 4250189 (1981-02-01), Hydes et al.
patent: 4533502 (1985-08-01), Rochon et al.
patent: 4571335 (1986-02-01), Taylor et al.
DeAlmeida Sergio G.
Farrell Nicholas
Hacker Miles P.
McCormack John J.
Hendrickson Stuart L.
Shaver Paul F.
University of Vermont and State Agricultural College
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