Compounds and methods for inhibition of HIV and related viruses

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514352, 546261, 546262, 546305, C07D40112, A61K 3144

Patent

active

057145032

ABSTRACT:
Treatment of AIDS, inhibition of the replication of HIV and related viruses thereof, and formulations using thiourea derivative compounds or salts thereof is disclosed. Also disclosed are novel thiourea derivative compounds.

REFERENCES:
patent: Re31244 (1983-05-01), Peterson
patent: 3061640 (1962-10-01), Beaver et al.
patent: 3705903 (1972-12-01), Crank
patent: 3809755 (1974-05-01), Crank
patent: 3891769 (1975-06-01), Shea et al.
patent: 3950537 (1976-04-01), DeBenneville et al.
patent: 3950538 (1976-04-01), Shea
patent: 4036979 (1977-07-01), Asato
patent: 4048333 (1977-09-01), Galabov et al.
patent: 4057636 (1977-11-01), Peterson
patent: 4066695 (1978-01-01), Cohen et al.
patent: 4096276 (1978-06-01), Cohen et al.
patent: 4113776 (1978-09-01), Cohen et al.
patent: 4150138 (1979-04-01), Cohen et al.
patent: 4169154 (1979-09-01), Cohen et al.
patent: 4367226 (1983-01-01), Foye
patent: 4656026 (1987-04-01), Coffmann et al.
patent: 4880836 (1989-11-01), Elbaum
patent: 4994481 (1991-02-01), Zimmer et al.
Zhang, Antiviral Res. 28 (4) 331, 1995.
Kammuller et al., Int'l Jour. of Immunopharmacology, 997-1010 (1988).
Lombardino et al., Jour. of Medicinal Chemistry, 7, No. 1, 97-101 (Jan. 1964).
Ghomeim et al., Egypt. J. Pharm. Sci. 28, No. 1-4, 77-86 (1987).
Fujiwara et al., J. Chem. Soc. Perkin Trans. 2, 1573-1577 (1980).
Fujiwara et al., J. Chem. Soc. Perkin Trans. 2, 659-663 (1979).
Chemical Abstracts, 94, No. 17, p. 766, Abstract No. 139811z (Apr. 27, 1981).
Chemical Abstracts, 90, No. 7, p. 107, Abstract No. 49009g (Feb. 12, 1979).
Nowak, Roczniki Chimii, 47, No. 12, 2377-2378 (1973).
Rahman et al., Bangladesh J. Biol. Science, 5, No. 1, 28-30 (1976).
Marx et al., J. of Medicinal Chem., 13, No. 6, 1179-1181 (1970).
Mammo et al., J. of Pharmacy and Pharmacology, 34, No. 11, 752-754 (1982).
Chemical Abstracts, 110, No. 9, p. 653, Abstract No. 75501n (Feb. 27, 1989).
Horn et al., J. of Chromatography, No. 180, 111-118 (1979).
Pataki, Chimia, 18, No. 1, 23-34 (1964).
Waite, Analytical Biochemistry, 192, No. 2, 429-433 (1991).
Lilova et al., Biological Chemistry Hoppe-Seyler, 367, No. 10, 1055-1059 (1986).
Attia et al., Bull. De L'Academie Polonaise Des Sciences, 24, No. 10, 781-790 (1976).
Korohoda et al., Polish J. of Pharmacology and Pharmacy, 28, No. 5, 423-427 (1976).
Weygand et al., European J. of Biochem., 20, 72-80 (1971).
Burrell et al., Australian J. of Chem., 28, No. 10, 2289-2298 (1975).
Mahachi et al., J. of Chromatography, No. 298, 279-288 (1984).
Miyano et al., Biomedical Chromatography, 2, No. 4, 139-144 (1987).
Chemical Abstracts, 60, No. 11, p. 1964, Abstract No. 13546f (May 25, 1964).
Knoppova et al., Collection of Czech. Chemical Comm., 39, No. 3, 773-778 (1974).
Epp, Analytical Chemistry, 29, No. 9, 1283-1287 (Aug. 23, 1957).
Solyom et al., Acta Chimica Academiae Scientarum Hungaricae, 68, No. 1-2, 93-132 (1971).
Chemical Abstracts, 76, No. 23, p. 46, Abstract No. 135847w (Jun. 5, 1972).
Chemical Abstracts, 111, No. 25, p. 854, Abstract No. 233511t (Dec. 18, 1989).
Chemical Abstracts, 112, No. 7, p. 14, Abstract No. 48249w (Feb. 12, 1990).
Chemical Abstracts, 95, No. 19, p. 731, Abstract No. 16907v (Nov. 9, 1981).
Martin et al., Archiv Der Pharmazie, 296, No. 10, 641-650 (Oct. 1963).
Birr et al., Angew. Chemie, 82, No. 18, 771-772 (1970).
Morikawa et al., Agricultural and Biological Chemistry, 55, No. 11, 2751-2756 (Nov. 1991).
A. Mohsen et al., J. Pharm. Sciences, vol. 73, No. 8, (1984) pp. 1166-1168.
Ware, E., Chem. Rev., 46, 436 (1950).
Central Patents Index Country Alerting Bulletin, Section B, 1979, Week B11, 27 Apr. 79, J5 4016-467.
H. Wilitzer et al., Pharmazie 33, H.1 (1978), pp. 30-38.
Chemical Abstracts, vol. 89, 1878, p. 644 (24221m).
Chemical Abstracts, vol. 94, 1981, p. 160 (26081t).
Chemical Abstracts, vol. 96, 1982, p. 52221 (52221Z).
Synthesis, May 1983, No. 5, pp. 391-392.
Indian J. Chem., vol. 10, pp. 686-690 (Jul., 1972).
Arch. Pharm. (Weinheim), vol. 323, pp. 971-975 (1990).
Jour. Pharm. Sci., vol. 51, No. 11, pp. 1031-1033 (Nov., 1962).
Indian J. Chem., vol. 21B, pp. 750-752, (Aug., 1982).
Chemical Abstracts, vol. 81, No. 21, (Nov. 25, 1974) Abstract No. 135582j and ZH. Org. Khim., vol. 10, No. 8, pp. 1661-1669 (1974).
Chemical Abstracts, vol. 83, No. 7, (Aug. 18, 1975) Abstract No. 53854b and Yakagaku Zasshi, vol. 95, No. 4, pp. 373-377 (1975).
Chemical Abstracts, vol. 70, No. 17 (Apr. 28, 1969) Abstract No. 77857n and Yakugaku Zasshi, vol. 88, No. 11, pp. 1428-1432 (1968).
Chemical Abstracts, vol. 62, No. 9 (Apr. 26, 1965) Abstract No. 10425d and Atti Accad. Sci. Lettere Arti Palermo, Pt. I, vol. 23, pp. 139-142 (1964).
Chemical Abstracts, vol. 65 (1966) Abstract No. 2907F and Bruce, M. et al. Cytokinin activity of some substituted ureas and thioureas, pp. 249-265 (Dec. 29, 1965).
Boll. Chim. Farm., F. Russo, vol. 100, pp. 252-256 (1961).
Indian Jour. Chem., Nagarajan, K. et al., vol. 23B, pp. 342-362 (Apr. 1984).
Jour. Med. Chem., vol. 15, No. 10, pp. 1082-1084 (1972).
Indian Jour. Chem., vol. 5, No. 4, pp. 145-146 (Apr. 1967).
Jour. Indian Chem. Soc., vol. 35, No. 4, pp. 245-248 (1961).
Indian Jour. Pharm. Sci., vol. 44, No. 1, pp. 83-85 (1982).
Chemical Abstract 81: 13558Z R.N. 53578-59-9.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compounds and methods for inhibition of HIV and related viruses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds and methods for inhibition of HIV and related viruses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and methods for inhibition of HIV and related viruses will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-662671

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.