Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-08-09
1998-02-03
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 14, 530323, 530327, 530345, 530409, C07K 702
Patent
active
057144648
ABSTRACT:
A substantially pure compound extracted from the mushroom Rozites caperata is disclosed. The compound disclosed is SEQ ID NO:1, a twelve amino acid peptide, covalently linked by the epsilon amino group of a carboxy terminal lysine to the carboxyl terminus of SEQ ID NO:2, or a pharmaceutically acceptable nontoxic salt of the compound. The disclosed compound inhibits replication of viruses having lipid bilayer envelopes. Also disclosed is a method for inhibiting replication of viruses having lipid bilayer envelopes. According to the method, such viruses can be inhibited by administering an effective amount of a substantially pure compound, which is SEQ ID NO:1 covalently to SEQ ID NO:2, or a pharmaceutically acceptable nontoxic salt of the compound.
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Brandt Curtis R.
Piraino Frank
Delaney Patrick R.
Tsang Cecilia J.
Wisconsin Alumni Research Foundation
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