Surgery – Truss – Pad
Patent
1987-05-21
1988-07-12
Coven, Edward M.
Surgery
Truss
Pad
128766, 128623, A61M 3100
Patent
active
047563141
ABSTRACT:
An improved fluid collection patch is disclosed which is capable of providing a quantitative indication of the average concentration of an agent in a body fluid during a collection period. The patch covers a predetermined area of a fluid secretory body surface such as the skin or mucous membrane and is provided with means for maintaining the flow of fluid into the patch substantially constant during the collection period. Preferred flow control means comprise an osmotic agent in the fluid flow path separated from the body surface by a semipermeable membrane. In a preferred embodiment the patch is adhesively bonded to the skin to collect sweat.
REFERENCES:
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3916899 (1975-11-01), Theeuwes
patent: 4014334 (1977-03-01), Theeuwes et al.
patent: 4077407 (1978-03-01), Theeuwes et al.
patent: 4329999 (1982-05-01), Phillips
Heyer et al, "Effect of . . . Solutes . . . on Osmotic Flow", Yale Jrnl. Bio & Med., Dec.-Feb. 1970, pp. 139-153.
Peck et al, "Continuous Drug Collection", Jrnl. Pharm. & Biopham., vol. 9, No. 1, 1981, pp. 41-57.
Phillips et al, "Long-Term Sweat Collection", Jrnl. Inst. Derm., vol. 68, No. 4, 1977, pp. 221-224.
Phillips, "Improved Adhesive Patch", Bio. Mat. Med. Dev. Art Org., 81, pp. 13-21, 1980.
Boher, "Measurement of Water Loss", Arch. Derm.-vol. 96, 1967, pp. 441-452.
Eckenhoff James B.
Theeuwes Felix
ALZA Corporation
Coven Edward M.
Mandell Edward L.
Precivale Shelley G.
Stone Steven F.
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