Therapeutic methods employing cyclic aminophosphonic acids

Details Therapeutic methods employing cyclic aminophosphonic acids Therapeutic methods employing cyclic aminophosphonic acids

1975-08-01

1976-10-05

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424 49, 424 54, A61K 31675, A61K 716, A61K 722

Patent

active

039845435

ABSTRACT:
Therapeutic methods employing cyclic aminophosphonic acids having the formula ##EQU1## wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 6 carbon atoms and n is an integer from 1 to 4; as well as their water-soluble salts. The cyclic aminophosphonic acids are excellent sequestering agents especially for alkaline earth metal ions, useful in cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficulty soluble calcium salts in the animal body.

REFERENCES:
patent: 3678164 (1972-07-01), Francis
patent: 3719756 (1973-03-01), Francis
Russell et al., Cale. Tiss. Res. 6, pp. 183-196 (1970) by Springer-Verlag 1970.
Fleisch et al., Science, vol. 165, pp. 1262-1264 (reprinted), 1969, by the Amer. Assoc. for the Advancement of Sci.

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