Method for photo-altering a biological system to improve biologi

Details Method for photo-altering a biological system to improve biologi Method for photo-altering a biological system to improve biologi

1994-12-01

2000-08-01

Yu, Mickey

Surgery

Miscellaneous

Methods

604 4, A61B 1900

Patent

active

060951478

ABSTRACT:
Photodynamic therapy is a new adjunctive therapy for filtration surgery that does not use chemotherapy agents or radiation, but uses pharmacologically-active sensitizing compounds to produce a titratable, localized, transient, post operative avascular conjunctiva. A photosensitizing agent in a biological system is selectively activated by delivering the photosensitive agent to the biological system and laser activating only a spatially selected portion of the delivered photosensitive agent. The activated portion of the photosensitive agent reacts with the biological system to obtain a predetermined biological effect. As a result, an improved spatial disposition and effectuation of the biological effect by the photosensitive agent in the biological system is achieved.

REFERENCES:
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patent: 5432171 (1995-07-01), Sessler et al.
patent: 5439570 (1995-08-01), Sessler et al.
Gomer et al. "Treatment of Intra Ocular Tumors With Hematoporphyrin Derivative Photo Radiation Therapy" Photochem Photobiol 39 (Suppl), 73S, Jul. 1984.
Garrett et al. "Photodynamic Therapy (PDT) of Exprimental Ocular Melanoma With Silicon Naphthalocyanine (SINc) in Rabbits," Investigative Ophthamology and Visual Science 35 (4). p. 2120, May 1994.

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