Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl)

Details Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl) Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl)

1999-02-17

1999-10-12

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D285125

Patent

active

059657375

ABSTRACT:
The present invention provides a process for making thiadiazole sulfones. In particular, the present process is used to make 2-(methyl-sulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole using catalytic oxidation in the presence of a suitable oxidizing agent. A preferred oxidizing agent is hydrogen peroxide. The catalyst system used for the oxidation reaction is a mixture of boric acid and glacial acetic acid. The molar ratio of glacial acetic acid to 2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole is from about 0.1:1 to about 0.5:1.

REFERENCES:
patent: 3562284 (1971-02-01), Newman et al.
patent: 5856449 (1999-01-01), Prasad
Durst, T., in Comprehensive Organic Chemistry: Chapter 11.6, Barton and Ollis, Eds., Pergammon Press, Oxford, (month unavailable) 1979.

Affiliated with

Also associated with

Rating

Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl) does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl), we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Approach to the conversion of 2-(methylthio)-5-(trifluoromethyl) will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-654140