Medicinal composition and its use as antidepressive agent

Details Medicinal composition and its use as antidepressive agent Medicinal composition and its use as antidepressive agent

1978-05-30

1980-02-19

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424258, A61K 3133, A61K 3147

Patent

active

041894782

ABSTRACT:
What is disclosed are medicinal compositions, useful as anti-depressive agents, containing a compound of the formula; ##STR1## in which R.sub.1, R.sub.3 and R.sub.4, which may be identical or different, and represent hydrogen atoms or lower alkyl or aralkyl groups, and R.sub.2 and R.sub.2 ', which may be identical or different, represent hydrogen or halogen atoms, hydroxy or trifluoromethyl groups or lower alkyl, alkoxy or aralkoxy groups, it also being possible that two adjacent radicals form an alkylene-dioxy radical, and R.sub.5 represents a hydrogen or halogen atom, a hydroxy, trifluoromethyl or nitro group or a lower alkyl, alkoxy or aralkoxy radical, and their salts with acids (active substance A) together with 7-chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4 (3H,5H)-dione (active substance B), and their use as antidepressive agent.

REFERENCES:
patent: 3577424 (1971-05-01), Ehrhart et al.
Chem. Abst., 85-14126h (1976).
Chem. Abst., 85-14128Q (1976).
Chem. Abst., 85-14109J (1976).

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