Trialkyl-lock-facilitated polymeric prodrugs of amino-containing

Details Trialkyl-lock-facilitated polymeric prodrugs of amino-containing Trialkyl-lock-facilitated polymeric prodrugs of amino-containing

1997-12-30

1999-10-12

Richter, Johann

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Monomer contains oxygen

424 851, 424 852, 424 854, 530351, 530402, 548572, 558230, 558273, 560160, 560170, 560186, A61K 31765

Patent

active

059651199

ABSTRACT:
The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula: ##STR1## wherein: B is a leaving group or a residue of an amine-containing target moiety;

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