Derivatives of 7-aminocephalosporanic acid

Details Derivatives of 7-aminocephalosporanic acid Derivatives of 7-aminocephalosporanic acid

1979-04-23

1980-09-23

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 19, 424246, C07D50118

Patent

active

042244412

ABSTRACT:
Novel 3-acyloxymethyl-cephem compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen or an acyl group; X is a divalent group consisting of a carbon chain having 2 to 3 carbon atoms and a carbonyl or sulfonyl group at one terminal end thereof, said divalent group being either substituted or unsubstituted on the carbon chain; and Z is an organic acid residue, and salts thereof were found to be useful as starting materials for preparing cephalosporins of the formula: ##STR2## wherein R.sup.2 stands for a residue of a nucleophilic compound and R.sup.1 has the same meaning as above.

REFERENCES:
patent: 3920638 (1975-11-01), Bickel et al.
patent: 3931161 (1976-01-01), Buitar et al.
patent: 3932392 (1976-01-01), Johnson et al.
patent: 4166178 (1979-07-01), Tsushima et al.

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