Process for the preparation of substituted 3-amino-2 (benzoyl)-a

Details Process for the preparation of substituted 3-amino-2 (benzoyl)-a Process for the preparation of substituted 3-amino-2 (benzoyl)-a

1989-06-08

1991-04-30

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

546156, C07C22704

Patent

active

050119710

ABSTRACT:
Process for the preparation of substituted 3-amino-2-(benzoyl)-acrylic acid esters of the formula I ##STR1## in which R.sub.1 denotes an alkyl radical with 1 to 4 C atoms, X.sub.1 denotes halogen, in particular fluorine or chlorine, X.sub.2, X.sub.3, X.sub.4 and X.sub.5 denote hydrogen, halogen, in particular fluorine or chlorine, an alkyl radical having 1-4 C atoms or an alkoxy radical having 1-4 C atoms in the alkyl chain, by selectively reducing a substituted 2-cyano-3-hydroxy-3(phenyl)acrylic acid ester of the formula II ##STR2## in which R.sub.1, X.sub.1, X.sub.2, X.sub.3, X.sub.4 and X.sub.5 have the meaning given above, and a process for the preparation of intermediate products for antibacterially active compounds from these compounds.

REFERENCES:
patent: 3054822 (1962-09-01), Schorr et al.
patent: 4003933 (1977-01-01), Drake

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