Phospholipase A2 inhibitor

Details Phospholipase A2 inhibitor Phospholipase A2 inhibitor

1990-04-30

1991-04-30

Weimar, Elizabeth C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31182

Patent

active

050119524

ABSTRACT:
A compound of the formula: ##STR1## wherein the wave line means .alpha.-bond or .beta.-bond, which compound is useful as a phospholipase A.sub.2 inhibitor. Process for the production of the compound, pharmaceutical composition containing the compound, and a cell culture of a microorganism Thielavia terricola RF-143 producing the compound are also provided.

REFERENCES:
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Kolly et al., Chemical Abstracts, vol. 110, No. 13, 27 Mar. 1989, p. 672, Abstract No. 114635f.
Endo et al., Chemical Abstracts, vol. 91, No. 25, 17 Dec. 1979, p. 519, Abstract No. 209363u.
Kitahara et al., Chemical Abstract, vol. 96, No. 7, 15 Feb. 1982, p. 295, Abstract No. 48698t.
Kitahara et al., Chemical Abstracts, vol. 99, No. 5, 1 Aug. 1983, p. 506, Abstract No. 38273y.
Emmono, Bulletin of the Torrey Biotanical Club, vol. 57, No. 2, Feb. 1930, pp. 123-126.

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