FK-506 C.sub.10 -C.sub.24 process intermediates

Details FK-506 C.sub.10 -C.sub.24 process intermediates FK-506 C.sub.10 -C.sub.24 process intermediates

1989-08-28

1991-04-30

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549292, 549369, 549374, 556444, 556482, 556485, 560111, 560112, 560262, 568660, 568662, 568673, 568675, C07D30930, C07D31906, C07C 69767, C07C 4315

Patent

active

050119435

ABSTRACT:
A process is described for the improved synthesis of the optically pure C.sub.10 -C.sub.24 fragment of the macrolide structure of the immunosuppressant FK-506. This compound is also useful as an intermediate for preparing FK-506 derivatives.

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