Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-06-13
1991-04-30
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549 42, 549 43, 549 44, 549 45, 549267, 549343, 549345, 546 89, 546 90, 546 62, 514250, 514287, 514450, 514443, 514826, A61K 3144, A61K 31365, C07D32100, C07D49814
Patent
active
050118455
ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.5 represents C.sub.1 to C.sub.6 -alkyl or the group--(CH.sub.2).sub.n --Z--(CH.sub.2).sub.m --Ar wherein Z represents O, S or --CH.sub.2 --and Ar is phenyl, optionally substituted by one or two groups selected from the group consisting of hydrogen, C.sub.1 to C.sub.6 -alkyl, C.sub.1 to C.sub.6 -alkoxy, Cl,F,Br,I,NO.sub.2, CF.sub.3, CN, R.sup.6 -S(O).sub.x, R.sup.7 --CO--,(R.sup.8 R.sup.9)NCO-and phenyl, wherein x is 0, 1 or 2, and each R.sup.6, R.sup.7, R.sup.8 and R.sup.9 is independently C.sub.1 to C.sub.6 alkyl or two adjacent groups on Ar may form together an additional fused benzenoid ring; n and m independently represent integers of from 1 to 8; and ring Q represents one of the rings Q.sub.1, Q.sub.2, Q.sub.3 or Q.sub.4 below: ##STR2## X is N or C--R.sup.1 ; Y is N or C--R.sup.4 ;
REFERENCES:
patent: Re30241 (1980-03-01), Minatoya et al.
patent: 3644353 (1972-02-01), Leats et al.
patent: 3904671 (1975-09-01), Minatoya et al.
Blythin David J.
Ganguly Ashit K.
Shue Ho-Jane
Boxer Matthew
Nelson James R.
Raymond Richard L.
Russell Mark W.
Schering Corporation
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