Method of monitoring patient compliance with medications prescri

Details Method of monitoring patient compliance with medications prescri Method of monitoring patient compliance with medications prescri

1996-07-05

1997-07-29

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Nitrogen containing

Amine and quaternary ammonium

436106, 436107, 436108, 436109, 436110, 436112, 436113, 436114, 436115, 436116, 436117, 436118, 436816, 436901, G01N 3348

Patent

active

056521464

ABSTRACT:
A method of monitoring compliance of a patient that has been placed on a medication maintenance program with a prescribed medication dosage by determining a normalized urine medication concentration. An unadulterated urine sample is obtained from the patient. The urine medication concentration and urine specific gravity are measured. The normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine and the urine specific gravity. The calculated normalized urine medication concentration is compared with an expected medication concentration value for the patient for the maintenance program prescribed to determine any significant differences therebetween as an indication of noncompliance. Alternatively, a urinary-parameter normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine, the urine specific gravity and at least one selected pharmacokinetic parameter of the medication. The calculated urinary-parameter normalized urine medication concentration is compared with an expected medication concentration value for an average compliant patient for the maintenance program prescribed to determine any significant differences therebetween as an indication of noncompliance.

REFERENCES:
patent: 2564247 (1951-08-01), Carson et al.
patent: 3856469 (1974-12-01), Schneider et al.
patent: 3901655 (1975-08-01), Shukla et al.
patent: 4104367 (1978-08-01), Gomez et a.
patent: 4196185 (1980-04-01), Focella et al.
patent: 5047329 (1991-09-01), Suzuki
patent: 5137692 (1992-08-01), Fritz
patent: 5179027 (1993-01-01), Fisher
patent: 5547878 (1996-08-01), Kell
Balabanova, et al Methadone distribution in blood, cerebrospinal fluid, urine and organ tissues EMBASE No. 92091431 Austria 1991.
Nilsson et al Effect of Urinary pH on the disposition of methadone in man EMBASE No. 82171209 W. Germany 1982.

Affiliated with

Also associated with

Rating

Method of monitoring patient compliance with medications prescri does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of monitoring patient compliance with medications prescri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of monitoring patient compliance with medications prescri will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-633058