Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-18
1996-04-30
Dees, Jose
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514396, A61K 31415
Patent
active
055125913
ABSTRACT:
Identified are particular class of imidazoles that inhibit anglogenesis. These imidazoles can be used to beneficially treat a variety of angiogenic conditions.
REFERENCES:
patent: 3678030 (1972-07-01), Yamazaki et al.
patent: 3901908 (1975-08-01), Fitzi et al.
patent: 3940486 (1976-02-01), Fitzi
patent: 4073922 (1978-02-01), Wybum-Mason
patent: 4119723 (1978-10-01), Wybum-Mason
patent: 4218449 (1980-08-01), Wybum-Mason
patent: 4491588 (1985-01-01), Rosenburg et al.
patent: 4569935 (1986-02-01), Rosenberg et al.
patent: 4657925 (1987-04-01), Horn
patent: 4758580 (1988-07-01), Numasaki et al.
patent: 4837333 (1989-06-01), Manley et al.
patent: 4886818 (1989-12-01), Numasaki et al.
patent: 4916118 (1990-04-01), Fidler et al.
patent: 4942162 (1990-07-01), Rosenberg et al.
patent: 5057530 (1991-10-01), Barner et al.
patent: 5059590 (1991-10-01), Ueda et al.
patent: 5132315 (1992-07-01), Kohn et al.
patent: 5358959 (1994-10-01), Halperin et al.
Marie Elisabeth Forque-Lafitte, Anne-Marie Coudray, Dominique Fagot, and Jan Mester--"Effects of Ketoconazole on the Proliferation and Cell Cycle of Human Cancer Cell Lines", Cancer Research 52, 6827-6831, Dec. 15, 1992.
CA101:183620y (1984).
CA116:187584x (1992).
CA106:209231c (1987).
George N. Tzanakakis, MD., Kailash C. Agarwal, PhD., Michael P. Vezeridis, MD.--"Inhibition of Hepatic Metastasis From a Human Pancreatic Adenocarcinoma (RWP-2) in the Nude Mouse by Prostacyclin, Forskolin, and Ketoconzzole," Cancer, vol. 65, Feb. 1, 1990.
Patricia A. Nardone, M.D., Gus J. Slotman, M.D., and Michael P. Vezeridis, M.D., "Ketoconazole: A Thromboxane Synthetase and 5-Lipoxygenase Inhibitor with Antimetastatic Activity in B16-F10 Melanoma," Journal of Surgical Research 44, 425-429 (1988).
Brugnara Carlo
Halperin Jose
Dees Jose
Frazier Barbara S.
President and Fellows of Harvard College
LandOfFree
Treatments for diseases characterized by neovascularization does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatments for diseases characterized by neovascularization, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatments for diseases characterized by neovascularization will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-629095