Device for controlled diffusion of a chemical substance

Details Device for controlled diffusion of a chemical substance Device for controlled diffusion of a chemical substance

1991-06-03

1994-08-02

Isabella, David

Surgery

Controlled release therapeutic device or system

604289, 128632, 422 681, 422 69, 433 80, 433 94, 433136, 433138, A61K 922, A61M 3500, A61C 1706, A61B 500

Patent

active

053341899

ABSTRACT:
A device and methods of use and manufacture are disclosed for controlled diffusion of chemical substances of interest intraorally. The device includes ported structure formed of material that is substantially impermeable to the substance of interest, an inner wall of which defines a compartment communicating through the ports with the exterior of the device. A dispersed layer is formed in the compartment of material having limited permeability, the layer being formed so that contact is maintained with the inner wall across the ports after formation, the ports and the layer thus providing a region of permeability to diffusion of the chemical substance of interest. In use, either the chemical substance of interest or a composition capable of binding itself to the chemical substance of interest is placed in the compartment and the device is positioned in the mouth of a subject where it may remain for extended periods.

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"Cellulose acetate tubular membrane", Chemical Abstracts, 87:24360.

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