Compositions containing 2-acetyl-1-pyrroline

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical

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424435, 424438, 424434, 424440, 424441, 424442, 424464, 424468, 424484, 424488, 424489, 426 5, 426 48, 426 94, 426 96, 426103, 426250, 426496, 426502, 426537, 426540, 426548, 426549, 426560, 426588, 426650, 426651, 426658, 426804, 536103, 548565, 514 23, 514 58, 514494, 514777, 514849, 514888, 514889, 514937, 514948, 514964, 514965, 514974, A61F 1300, A61K 968

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active

055122906

ABSTRACT:
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with an acid to obtain a reaction medium, adding an equimolar amount of a base to the reaction medium to obtain a neutralized reaction medium containing 2-acetyl-1-pyrroline, combining maltodextrin and/or cyclodextrin with the neutralized reaction medium to obtain a support solution and freeze-drying the support solution to obtain the composition.

REFERENCES:
patent: 3620771 (1971-11-01), Hunter
patent: 3725425 (1973-04-01), Hunter
patent: 4522838 (1985-06-01), Buttery et al.
patent: 5087461 (1992-02-01), Levine et al.
patent: 5206025 (1993-04-01), Courteille et al.
patent: 5280127 (1994-01-01), Duby et al.
No. 84327 D/46 of Japanese Patent No. J5 6125-364 (1980).
Buchi, et al., "Synthesis of 2-Acetyl-1,4,5,6-tetrahydro-pyridine, A Constituent of Bread Aroma," J. Org. Chem., vol. 36, No. 4, 1971, 609-610.
Buttery, et al., "Cooked Rice Aroma and 2-Acetyl-1-Pyrroline," J. Agric. Food Chem., 1983, 31, 823-826.

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