Method of treating skin injuries using thromboxane A.sub.2 recep

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514562, 514568, 514570, 514571, A61K 3134, A61K 3119, A61K 31195

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active

049258737

ABSTRACT:
A method for treating skin injuries is provided by administering a thromboxane A.sub.2 receptor antagonist systemically or topically to the skin area to be treated.

REFERENCES:
patent: 4416896 (1983-11-01), Nakane et al.
patent: 4663336 (1987-05-01), Nakane et al.
patent: 4673685 (1987-06-01), Varma et al.
R. Rees et al., Mechanism of Platelet Injury Associated with Dermonecrosis Resulting from Brown Recluse Spider Vernom., Clinical Research, 30:265A, 1982.
E. J. Del Beccar et al., The Use of Specific Thromboxane Inhibitors to Preserve the Derman Microcirculation After Burning, Surgery, 87(2):137-141, 1980.
S. Lelcuk et al., Prostacyclin (PG12) and Thromboxane (Tx)A2: Mediators of Wound Healing, Isr. J. Med. Sci., (23, No. 7, 841-43, 1987).
J. P. Heggers et al., Histological Demonstration of Prostaglandins and Thromboxanes in Burned Tissue, Journal of Surgical Research, 28(2):110-117, 1980.
M. C. Robson et al., A New Explanation for the Progressive Tissue Loss in Electrical Injuries, Plastic and Reconstructive Surgery, 73(3):431-437, 1984.
M. C. Robson et al., The Effect of Prostaglandins on the Dermal Microcirculation After Burning, and the Inhibition of the Effect by Specific Pharmacological Agents, Plastic and Reconstructive Surgery, 63(6):781-787, 1979.
L. S. Zachary et al., Combined Prostacyclin and Thromboxane Synthetase Inhibitor UK 38485 in Flap Survival, Annals of Plastic Surgery, 17(2):112 -115, 1986.
J. Backon, Use of a Novel Thromboxane Synthetase Inhibitor in Burns, Burns Incl. Therm. Inj. (England), Jun., 1987, 13(3), p. 252.
J. P. Heggers et al., Thromboxane Inhibitors for the Prevention of Progressive Dermal Ischemia due to the Thermal Injury, J Burn Care Rehabil., Nov.-Dec., 1985, 6(6), pp. 466-468.
S. L. Wang et al., The Effect of the Thromboxane Synthetase Inhibitor Dazmegrel (UK-38,485) on Wound Healing, Dermal Ink Perfusion and Skin Blood Flow Measurements in Deep Partial Thickness Burns, Burns Incl. Therm. Inj., Jun. 1986, 12(5), pp. 312-317.
M. C. Robson et al., Increasing Dermal Perfusion After Burning by Decreasing Thromboxane Production, J Trauma, Sep. 1980, 20(9), pp. 722-725.
J. R. Saranto et al., Blisters, Cooling, Antithromboxanes, and Healing in Experimental Zone-of-Stasis Burns, J Trauma, Oct. 1983, 23(10), pp. 927-933.
F. Alexander et al., Arachidonic Acid Metabolites Mediate Early Burn Edema, J Trauma, Aug. 1984, 24(8), pp. 709-712.
R. L. McCauley et al., Frostbite Injuries: A Rational Approach Based on the Pathophysiology, J Trauma, Feb. 1983, 23(2), pp. 143-147.

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