Novel spiro-oxazolidinediones

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548216, C07D26344, A61K 3142

Patent

active

042268753

ABSTRACT:
Novel spiro-oxazolidinediones useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. Pharmaceutical compositions containing the novel compounds and a method of treating chronic diabetic complications are also disclosed.

REFERENCES:
R. W. Stoughton, J.A.C.S. 63, 2376, (1941).
J. W. Clark-Lewis, Chemical Reviews 58, 63, (1958).
M. A. Spielman, J.A.C.S. 66, 1244, (1944).
H. Najer et al., Bull. Soc. Chim., Fr. 1961, 1226, (1961).

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