Preparation of phenyl-substituted epoxides

Details Preparation of phenyl-substituted epoxides Preparation of phenyl-substituted epoxides

1988-08-25

1990-06-12

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549520, 549522, C07D30102

Patent

active

049334778

ABSTRACT:
Phenyl-substituted epoxides of the formula ##STR1## where R.sup.1 and R.sup.2 are each hydrogen, alkyl, alkenyl, phenyl, halogen, nitro, alkoxy, haloalkyl, phenoxy or phenylsulfonyl, are prepared by reducing a haloacetophenone to a halohydrin and reacting the halohydrin with an alkali metal hydroxide by a process in which the reduction with the alkali metal borohydride and the reaction are carried out in aqueous organic solution, or the cyclization of a halohydrin with an alkali metal hydroxide is carried out in an organic liquid.

REFERENCES:
patent: 2237284 (1941-04-01), Alquist et al.
patent: 2816059 (1957-12-01), Mills
patent: 2887509 (1959-05-01), Nash
Wierenga et al, J. Org. Chem. 49 (1984), pp. 438-442.
Chapman et al, J. Chem. Soc. (C) 1967, pp. 293-296.

Affiliated with

Also associated with

Rating

Preparation of phenyl-substituted epoxides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of phenyl-substituted epoxides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of phenyl-substituted epoxides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-618243