Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1984-01-11
1985-09-03
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
546272, 548453, C07D47104, C07D48704, C07D49804, C07D51304
Patent
active
045394008
ABSTRACT:
The invention provides new derivatives of the formula: ##STR1## in which either (a) Y=COOH or a radical of the formula (II), in which R.sub.2 =alkyl or benzyl, A=a sulphur atom, m=1, n=0, R=pyridin-3-yl and R.sub.1 =H, or (b) Y=CN, COOH or a radical of the formula ##STR2## defined as above, A=S, O or CH.sub.2, m=1 or 2 and n=0, 1 or 2, (m+n) being 1, 2 or 3, R=H, alkyl or phenyl (optionally substituted by halogen, alkyl, alkoxy or CF.sub.3) and R.sub.1 =a radical of the formula ##STR3## in which p=0 or 1, the alkyl radicals and alkyl portions being straight-chain or branched-chain and containing 1 to 4 carbon atoms each. Processes for the production of these compounds are described. They are useful as intermediates for the preparation of new medicaments.
REFERENCES:
patent: 3544590 (1970-12-01), Kittleson
patent: 3865839 (1975-02-01), Allen et al.
Percy et al., C.A., vol. 75, 1971, 75: 96775d, p. 174.
Fabre Jean-Louis
Farge Daniel
James Claude
Lave Daniel
Jiles Henry R.
Mullins J. G.
Rhone-Poulenc Sante
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