Metachromatic dye sorption and fluorescent light emmisive means

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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424 71, G01N 3100, G01N 100

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045005095

ABSTRACT:
Differentiation, identification and enumeration of dye responsive human blood cells essential to diagnosis and prognosis of certain diseases is established by preparation of the reaction product of a human blood specimen of the patient in an aqueous fixative-free environment at blood temperatures with selected basic, cationic quaternary dyes, particularly basic orange #21. The so-prepared specimen becomes instantly responsive to emissive wave energy source exposure to stimulate reproducible fluorescent light emission from all of said dye responsive cells. The quantum of said fluorescent light energy emitted provides individual sets of data response relative to hue, value, chroma and intensity to permit differentiation, identification and enumeration of all of said dye responsive components in said blood specimen. By use of a bi-modal wave energy system involving additional use of white light wave energy absorbance, independent sets of data can provide both confirmatory and ancillary information.

REFERENCES:
patent: 2126852 (1938-08-01), Wolff
patent: 3560135 (1971-02-01), Yamayo
patent: 3617185 (1971-11-01), Drautz
patent: 3916205 (1975-10-01), Kleinerman
patent: 3961039 (1976-06-01), Sternheimer
patent: 3985500 (1976-10-01), Streck
patent: 4146604 (1979-03-01), Kleinerman
Gurr, Synth. Dyes in Biol. Med. & Chem., Acd. Press, NY, 1971, pp. 54, 55, 90, 117, 147-149, 395, 805.
Conn's Biol. Stains, Williams & Wilkins, Baltimore, 9th ed., 1977, pp. 43, 368, 404-407, 415-428.
Gray, The Ency. of Microscop. & Microtech., Van Nostrand-Reinhold Co., N.Y., 1973, pp. 398-399, 469, 551, 563.
Humason, Animal Tissue Tech., W. H. Freeman & Co., San Francisco, 1972, pp. 128-132.
Hallberg, Acta Med. Scand., Suppl., vol. 180, 1946, pp. 7-15.
Pilot, Use of Base Fluids for Counting Eosinophils, U. of Ill., May 23, 1950, pp. 870-871.
Kodak Adv., Sci. Amer., May 1976, p. 49.
Ruddell, J. Invertebr. Pathol., vol. 31, 1978, pp. 313-323.
Williams, J. of Lab. & Clin. Med., vol. VIII, Oct. 1922-Sep. 1923, pp. 250-253.
Ruddell, Chem. Abs., vol. 89, 1978, Ab. No. 89:54252q; Chem. Sub. Index, p. 2791cs.
Simpson, Stain Tech., vol. 45, No. 5, 1970, pp. 221-223.
MacConaill, Ireland J. Med. Sci., Jun. 1964, pp. 243-250.
Sabin, Bull. Johns Hopkins U., vol. XXXIV, No. 391, Sep. 1923, pp. 277-288.
Spiridonovitch, The Anatomical Record, vol. 26, Jan-May 1924, pp. 367-373.
Moore, PSEBM, vol. 82, 1953, pp. 601-603.

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