Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-06-23
1977-12-20
Rosen, Sam
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260455A, 424304, A61K 3127, A61K 31275, C07C15300
Patent
active
040642658
ABSTRACT:
The present invention relates to new dithiocarbamic acid esters having the formula ##STR1## wherein R.sub.1 represents a phenyloxyphenyl or phenylaminophenyl radical which is unsubstituted or substituted by lower alkyl, halogen, trifluoromethyl, nitro or cyano, R.sub.2 represents hydrogen or lower alkyl, and alk represents lower alkylidene or lower alkylene, and also to salts of compounds of the formula (I), wherein R.sub.2 represents hydrogen, with pharmaceutically acceptable bases. These new compounds possess a strong anthelminthic activity and are useful for the treatment of warm-blooded animals infected with parasitic helminths. A specific embodiment is the N-[4-(4-nitroanilino)-phenyl]-dithiocarbamic acid-(2-carboxyethyl)-ester.
REFERENCES:
patent: 3923854 (1975-12-01), Duerr
Aufderhaar Ernst
Schweizer Ernst
Varsanyi Denis V.
Ciba-Geigy Corporation
Groeger Theodore O.
Rosen Sam
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