15-Ethynyl-PGE.sub.1

Details 15-Ethynyl-PGE.sub.1 15-Ethynyl-PGE.sub.1

1976-08-25

1977-12-20

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

560121, C07C17700

Patent

active

040641651

ABSTRACT:
7-(2.beta.-[(3S)-3-Ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.-hydroxy-5-ox o-1.alpha.-cyclopentyl)-cis-5-heptenoic acid, 2.beta.-[(3S)-3-ethynyl-3-hydroxy-trans-1-octenyl]-3.alpha.-hydroxy-5-oxo- 1.alpha.-cyclopentane heptanoic acid, related compounds, and intermediates thereto are disclosed. The final products have activity as bronchodilators and in reducing gastric secretion.

REFERENCES:
patent: 3922302 (1975-11-01), Strike
patent: 4001314 (1977-01-01), Husbands

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