Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-10-28
1977-12-20
Coughlan, Jr., Paul M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26032625, 2603265B, 26032662, 2603269, 424274, C07D48704
Patent
active
040641392
ABSTRACT:
Substituted 9,10-dihydroanthracen-9,10-imines are disclosed to be minor tranquilizers, anticonvulsnts, muscle relaxants, and to be useful in the treatment of extrapyramidal disorders such as Parkinson's disease; also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions.
REFERENCES:
patent: 3678072 (1972-07-01), Klanderman et al.
patent: 3726897 (1973-04-01), Schindler et al.
Kricka et al., J. Chem. Soc., Perkins I, pp. 766-771 (1973).
Emmett et al., Tetrahedron 22, 1101, (1966).
Harrison et al., Tetrahedron 24, 4589, (1968).
Wittig et al., Annalen 630, 10 (1960).
Bolhuis et al., J. Chem. Soc. Chem. Comm. 870, (1974).
Anderson Paul S.
Christy Marcia E.
Ponticello Gerald S.
Coughlan, Jr. Paul M.
Merck & Co. , Inc.
Nicholson William H.
Tovar Jose
Westlake, Jr. Harry E.
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