Antimicrobial derivatives of 3-(1H-imidazol-1-yl)-2-propen-1-one

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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Other Related Categories

424263, 542440, 548341, A61K 31415

Type

Patent

Status

active

Patent number

043178316

Description

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein R.sup.1 is lower alkyl; phenyl-lower alkyl; phenyl; substituted phenyl wherein the phenyl group bears one or two halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, cyano or nitro groups; 5- or 6-membered monocyclic aromatic heterocyclics containing one hetero atom, namely, O, S or N, such as furanyl, pyridinyl or thiophenyl; and substituted heterocyclics wherein any of the above heterocyclics bears one halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, cyano or nitro group;

REFERENCES:
patent: 3929819 (1975-12-01), Inazuka et al.
patent: 4067989 (1978-01-01), Shephard et al.
Chemical Abstracts, 67:32647r (1967) Hoffmann, S., et al., Z. Chem., 7(1), 12(1967).
Chemical Abstracts, 56:11996b (1962) Schonbaum, G., et al., J. Biol. Chem., 236, 2930-2935 (1961).

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